Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363975 | 0.86 | MGAM (0.68) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL5161544 | 0.85 | MGAM (0.58) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL5160062 | 0.85 | MGAM (0.58) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL7100632 | 0.84 | MGAM (0.61) | MGAMCFTRHPGDSKDM4EKMT2A | |
| SCHEMBL8270577 | 0.84 | MGAM (0.65) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL529904 | 0.84 | MGAM (0.65) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL5163220 | 0.84 | MGAM (0.56) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL5160063 | 0.82 | MGAM (0.55) | MGAMCFTRHPGDSKDM4EKMT2A | |
| SCHEMBL29684771 | 0.82 | MGAM (0.71) | MGAMCFTRHPGDSMAP4K4CSNK1G2 | |
| SCHEMBL530761 | 0.82 | MGAM (0.71) | MGAMCFTRHPGDSMAP4K4CSNK1G2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| WO-1990007505-A1 | 2- AND 3-AMINOMETHYL-6-ARYLCARBONYL-2,3-DIHYDROPYRROLO[1,2,3-de]-1,4-BENZOXAZINES | STERLING DRUG INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4939138-A | 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |