Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.48 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100632 | 0.84 | MGAM (0.61) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL9700485 | 0.84 | MGAM (0.61) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL21296699 | 0.83 | MGAM (0.65) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL8270577 | 0.83 | MGAM (0.65) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL4817449 | 0.83 | MGAM (0.65) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL5363975 | 0.82 | MGAM (0.68) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL29362497 | 0.81 | MGAM (0.71) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL23372 | 0.81 | MGAM (0.71) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL12505008 | 0.81 | CFTR (0.68) | MGAMCFTRRAB9ATOP2ATOP2B | |
| SCHEMBL9361658 | 0.81 | MGAM (0.61) | MGAMCFTRRAB9ATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| EP-2471786-A1 | AMINOPYRAZOLE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-07-04 | — | — | EP | disclosed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011016528-A1 | AMINOPYRAZOLE DERIVATIVE | 中外製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |