SCHEMBL9700560

SCHEMBL9700560

CC(C)CS(=O)(=O)NC[C@@H](O)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7261445 0.95 REN (0.57) REN
SCHEMBL7301015 0.94 REN (0.54) REN
SCHEMBL9700464 0.93 REN (0.52) REN
SCHEMBL9700486 0.93 REN (0.52) REN
SCHEMBL9699536 0.90 REN (0.48) REN
SCHEMBL9699268 0.90 REN (0.64) REN
SCHEMBL9698229 0.90 REN (0.48) REN
SCHEMBL7272703 0.90 REN (0.57) REN
SCHEMBL7274996 0.89 REN (0.56) REN
SCHEMBL7275302 0.89 REN (0.56) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0501280-A2 Renin-inhibiting peptide analogues MERCK PATENT GmbH (DE) 1992-09-02 EP disclosed