Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216390 | 0.92 | RXFP1 (0.41) | RXFP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9201756 | 0.89 | NPC1 (0.48) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9701782 | 0.86 | POLB (0.39) | RXFP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9203715 | 0.85 | CHRM5 (0.44) | NPC1POLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9700664 | 0.83 | NPC1 (0.33) | RXFP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9700365 | 0.81 | POLB (0.40) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9700566 | 0.81 | HSD11B1 (0.36) | NPC1POLBHTTSMN1; SMN2HSD11B1 | |
| SCHEMBL9273002 | 0.81 | PARP1 (0.41) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9222286 | 0.81 | NPC1 (0.50) | RXFP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9123045 | 0.81 | NPC1 (0.50) | RXFP1NPC1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015310-A1 | USE OF TRICYCLIC ISOINDOLINONES AS ANTIVIRAL DRUGS, AND NEW, OPTICALLY ACTIVE ISOINDOLINONES | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-17 | — | — | WO | disclosed |