Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700745 | 0.88 | CYP1A2 (0.42) | CYP1A2CYP2C9HIF1A | |
| SCHEMBL9742575 | 0.88 | — | — | |
| SCHEMBL1429155 | 0.83 | — | — | |
| SCHEMBL9700620 | 0.78 | — | — | |
| SCHEMBL9701943 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL9742716 | 0.76 | TPH1 (0.33) | — | |
| SCHEMBL9701730 | 0.74 | — | — | |
| SCHEMBL9741731 | 0.73 | — | — | |
| SCHEMBL9345135 | 0.71 | MEN1 (0.56) | — | |
| SCHEMBL9702005 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |