Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.45 |
| ▸ | CTSE | P14091 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699532 | 0.93 | REN (0.47) | RENCTSECTSD | |
| SCHEMBL9700497 | 0.86 | REN (0.47) | RENCTSECTSDPGC | |
| SCHEMBL9699700 | 0.86 | REN (0.50) | REN | |
| SCHEMBL9699376 | 0.85 | REN (0.49) | RENCTSECTSD | |
| SCHEMBL9699260 | 0.85 | REN (0.48) | RENCTSECTSD | |
| SCHEMBL9700448 | 0.85 | REN (0.51) | REN | |
| SCHEMBL9699599 | 0.85 | REN (0.53) | RENCTSECTSD | |
| SCHEMBL9700398 | 0.85 | REN (0.51) | REN | |
| SCHEMBL9700613 | 0.85 | REN (0.49) | RENCTSECTSD | |
| SCHEMBL9699400 | 0.85 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501280-A2 | Renin-inhibiting peptide analogues | MERCK PATENT GmbH (DE) | 1992-09-02 | — | — | EP | disclosed |