Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405667 | 0.76 | MAOB (0.68) | FKBP1AMAOBNPC1RAB9AMAOA | |
| SCHEMBL28851447 | 0.75 | FKBP1A (0.62) | FKBP1AMAOBNPC1RAB9APKM | |
| SCHEMBL7024761 | 0.74 | MAOB (0.66) | MAOBNPC1RAB9AMAOAMAPT | |
| SCHEMBL9703320 | 0.74 | AGXT (0.54) | NPC1RAB9AALDH1A1POLBHPGD | |
| SCHEMBL3758230 | 0.73 | MAOB (0.61) | FKBP1AMAOBNPC1RAB9APKM | |
| SCHEMBL3758228 | 0.73 | MAOB (0.61) | FKBP1AMAOBNPC1RAB9APKM | |
| SCHEMBL3758225 | 0.73 | MAOB (0.61) | FKBP1AMAOBNPC1RAB9APKM | |
| SCHEMBL2729496 | 0.73 | FKBP1A (0.63) | FKBP1AMAOBNPC1RAB9APKM | |
| SCHEMBL8542594 | 0.73 | MAOB (0.64) | MAOBNPC1RAB9AMAOAMAPT | |
| Hydrochloric Acid SCHEMBL2947233 | 0.72 | MAOB (0.59) | FKBP1AMAOBNPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |