Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271340 | 0.82 | HRH4 (0.51) | HRH4PIK3CGPDE10APDGFRBPDGFRA | |
| SCHEMBL29234177 | 0.79 | KDM4E (0.42) | PDE10APDGFRBPDGFRAMEN1MAPT | |
| SCHEMBL29234175 | 0.79 | NQO2 (0.46) | PDE10AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL14322277 | 0.76 | HRH4 (0.47) | HRH4PIK3CGPDGFRBPDGFRANR4A2 | |
| SCHEMBL203068 | 0.76 | CCR1 (0.48) | PIK3CGPDE10APDGFRBPDGFRANR4A2 | |
| SCHEMBL29518426 | 0.76 | CCR1 (0.48) | PIK3CGPDE10APDGFRBPDGFRANR4A2 | |
| SCHEMBL17179175 | 0.75 | FGFR3 (0.47) | HRH4PIK3CGPDE10APDGFRBPDGFRA | |
| SCHEMBL346120 | 0.75 | ALDH1A1 (0.55) | HRH4PIK3CGPDGFRBPDGFRANR4A2 | |
| SCHEMBL27686 | 0.75 | PDE10A (0.69) | PDE10APDGFRBPDGFRAMEN1MAPT | |
| SCHEMBL30518375 | 0.75 | PDE10A (0.69) | PDE10APDGFRBPDGFRAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164962-A | Bis 1, 4-dihydropyridine derivative, and preparation method and application thereof | 河北科技大学 | 2024-06-11 | — | — | CN | disclosed |
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |