Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4116189 | 1.00 | HDAC4 (0.52) | HDAC4MMP2MMP9CA12CA1 | |
| SCHEMBL4711538 | 1.00 | HDAC4 (0.52) | HDAC4MMP2MMP9CA12CA1 | |
| SCHEMBL4760506 | 1.00 | HDAC4 (0.52) | HDAC4MMP2MMP9CA12CA1 | |
| SCHEMBL28037674 | 0.97 | MMP2 (0.52) | HDAC4MMP2MMP9CA12CA1 | |
| Maleic Acid SCHEMBL10698815 | 0.93 | HDAC4 (0.47) | HDAC4MMP2MMP9CA12CA1 | |
| SCHEMBL17772442 | 0.90 | SMYD3 (0.50) | NPC1RAB9ASMYD3KDM1AMAOA | |
| SCHEMBL775118 | 0.88 | SSTR3 (0.61) | MMP2MMP9MMP13SSTR3NPC1 | |
| SCHEMBL9539183 | 0.85 | MMP2 (0.53) | HDAC4MMP2MMP9CA12CA1 | |
| SCHEMBL774564 | 0.84 | MMP2 (0.59) | MMP2MMP9MMP13SSTR3NPC1 | |
| SCHEMBL22394702 | 0.84 | HDAC4 (0.53) | HDAC4MMP2MMP9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004017-A1 | CIS-N-(2-AMINOCYCLOHEXYL)BENZAMIDE AND THEIR ENANTIOMERS AS ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |