Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483888 | 0.84 | MIF (0.67) | MIFCYP3A4ALDH1A1CA2HSD17B10 | |
| Bitoscanate SCHEMBL11598436 | 0.79 | MIF (0.68) | MIFCYP3A4ALDH1A1CA2HSD17B10 | |
| SCHEMBL5721840 | 0.79 | CA12 (0.58) | CYP3A4ALDH1A1CA12CA2CA9 | |
| SCHEMBL5721846 | 0.79 | CA12 (0.58) | CYP3A4ALDH1A1CA12CA2CA9 | |
| SCHEMBL30940204 | 0.79 | CA12 (0.58) | CYP3A4ALDH1A1CA12CA2CA9 | |
| SCHEMBL9460699 | 0.78 | CYP3A4 (0.46) | CYP3A4ALDH1A1CA12CA2CA9 | |
| Carbon Dioxide SCHEMBL9270437 | 0.77 | CYP3A4 (0.44) | CYP3A4ALDH1A1CA12CA2CA9 | |
| SCHEMBL11053294 | 0.77 | MIF (0.44) | MIFCYP3A4ALDH1A1CA2HSD17B10 | |
| SCHEMBL14305109 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1CA2HSD17B10 | |
| SCHEMBL20337 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516848-B | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114516848-A | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516848-B | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114516848-A | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2022-05-20 | — | — | CN | disclosed |
| EP-2578584-B1 | ARYLAMINO PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | SI CHUAN UNIV (CN) | 2020-08-12 | — | — | EP | disclosed |
| CN-105832740-B | Aryl amine purine derivative and preparation method thereof and purposes in medicine | 石药集团中奇制药技术（石家庄）有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-105832740-A | Aromatic amino purine derivative as well as preparation method and pharmaceutical application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-9096601-B2 | Arylamino purine derivatives, preparation method and pharmaceutical use thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2015-08-04 | — | — | US | disclosed |
| US-20130203986-A1 | Arylamino Purine Derivatives, Preparation Method and Pharmaceutical Use Thereof | SI Chuaan University (CN) | 2013-08-08 | — | — | US | disclosed |
| EP-2578584-A1 | ARYLAMINO PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | Si Chuan University (CN) | 2013-04-10 | — | — | EP | disclosed |
| WO-1992000526-A1 | PEPTIDE SEQUENCING METHOD AND REAGENTS THEREFOR | GARIEPY KATHLEEN COX (US) | 1992-01-09 | — | — | WO | disclosed |
| US-4242122-A | CARBAMOYL-OXY AND -THIO DERIVATIVES OF PHENYLUREA | MONSANTO COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4089887-A | Process for the production of isothiocyanates | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4013450-A | Herbicidal ureido containing carbanilates | MONSANTO COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4000253-A | FUNGICIDES, BACTERICIDES, ALGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3996275-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3956384-A | HERBICIDE | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203986-A1 | Arylamino Purine Derivatives, Preparation Method and Pharmaceutical Use Thereof | EGFR, PNP, GART | MIF 3842/4885CYP3A4 1146/4885ALDH1A1 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.