SCHEMBL20337

SCHEMBL20337

Cc1cccc(N=C=S)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
HTR3E A5X5Y0 2/20 0.48
HTR3B O95264 2/20 0.48
HTR3A P46098 2/20 0.48
HTR3D Q70Z44 2/20 0.48
HTR3C Q8WXA8 2/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
NPC1 O15118 2/20 0.47
CASP3 P42574 2/20 0.47
RAB9A P51151 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
NSD2 O96028 1/20 0.47
ACHE P22303 3/20 0.46
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30298644 1.00 MIF (0.54) MIFHTR3EHTR3BHTR3AHTR3D
SCHEMBL8676885 0.89 MIF (0.44) MIFHTR3EHTR3BHTR3AHTR3D
SCHEMBL483888 0.84 MIF (0.67) MIFMEN1KMT2ATDP1MAPT
SCHEMBL6275073 0.82 HTR3E (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL9094629 0.80 ACHE (0.55) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL9094635 0.80 ACHE (0.55) HTR3EHTR3BHTR3AHTR3DHTR3C
Phenylisothiocyanate SCHEMBL28790260 0.80 MIF (0.77) MIFTDP1ACHECYP3A4P2RY6
Bitoscanate SCHEMBL11598436 0.79 MIF (0.68) MIFMEN1KMT2ATDP1MAPT
SCHEMBL11981455 0.79 MEN1 (0.67) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1405327 0.79 MEN1 (0.67) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
US-12193465-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-01-14 US claimed
CN-114516848-B Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2024-02-02 CN claimed
CN-117247409-A 3-thio/seleno-phosphorylated imidazole derivative and synthetic method and application thereof 曲阜师范大学 2023-12-19 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-20220225647-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
US-20220225646-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
CN-114516848-A Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2022-05-20 CN claimed
CN-109705146-B 2-aminobenzo [4, 5] thieno [3, 2-d ] thiazole, derivative and synthetic method thereof 湘潭大学 2021-05-04 CN claimed
CN-111875524-A Method for preparing isothiocyanate by base catalysis 西安近代化学研究所 2020-11-03 CN claimed
US-20160250175-A1 COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE JC (WUXI) COMPANY, INC. (CN) 2016-09-01 US claimed
EP-3034076-A1 COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE JC (Wuxi) COMPANY, Inc. (CN) 2016-06-22 EP claimed
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO claimed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US claimed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160250175-A1 COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE CHUK, KIT, MKI67 MIF 986/4885HTR3E 2361/4885HTR3B 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.