Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702808 | 0.93 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9701118 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9701434 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9702671 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9702254 | 0.82 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8567083 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9702879 | 0.81 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9701240 | 0.80 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8972305 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9701125 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497516-A1 | Substituted pyrrolo-fused 6-membered heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5124335-A | Hypotensive agents, antiglaucoma agents | MERCK & CO., INC. (US) | 1992-06-23 | — | — | US | disclosed |