Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024443 | 0.89 | MRGPRX4 (0.38) | CYSLTR1GPBAR1KDR | |
| SCHEMBL2745018 | 0.87 | PPARG (0.41) | PPARGPPARACYSLTR1LTA4H | |
| SCHEMBL31124766 | 0.85 | TSHR (0.35) | TTRPPARGPPARAGPBAR1LTA4H | |
| SCHEMBL7985831 | 0.83 | VDR (0.35) | PPARGPPARA | |
| SCHEMBL1587700 | 0.81 | KDR (0.33) | TTRPPARGPPARALTA4HKDR | |
| SCHEMBL5672882 | 0.80 | SMN1; SMN2 (0.35) | TTRPPARGPPARA | |
| SCHEMBL16818604 | 0.80 | TACR1 (0.34) | PPARGPPARA | |
| SCHEMBL9347235 | 0.79 | ESR1 (0.43) | PPARGCYP1A2 | |
| SCHEMBL5106543 | 0.79 | CYP4F2 (0.42) | PPARGGPBAR1LTA4HKDRCYP1A2 | |
| SCHEMBL30718622 | 0.79 | TEC (0.39) | CASRACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005153-A1 | ANTIPROLIFERATIVE SUBSTITUTED NAPHTHALENE COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1992-04-02 | — | — | WO | disclosed |