SCHEMBL9701512

SCHEMBL9701512

Cc1cc(C(C(=O)O)c2ccccc2)cc(C)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TTR P02766 1/20 0.43
ALOX5 P09917 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
CYP2D6 P10635 1/20 0.42
SRC P12931 1/20 0.42
NPC1 O15118 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11690953 0.90 CA1 (0.44) L3MBTL1MEN1KMT2ATTRALOX5
SCHEMBL27965914 0.82 L3MBTL1 (0.50) L3MBTL1MEN1KMT2ACYP2D6NPC1
Diphenylacetic Acid SCHEMBL11774892 0.80 SRC (0.56) L3MBTL1KMT2ATDP1CYP2D6SRC
Diphenylacetic Acid SCHEMBL38022 0.79 SRC (0.62) L3MBTL1MEN1KMT2APTGS1TDP1
Diphenylacetic Acid SCHEMBL8513250 0.79 SRC (0.62) L3MBTL1MEN1KMT2APTGS1TDP1
SCHEMBL10442632 0.77 BCL2 (0.40) MEN1KMT2ATTRALOX5PTGS1
Diphenylacetic Acid SCHEMBL6852183 0.77 SRC (0.59) L3MBTL1MEN1KMT2APTGS1TDP1
Diphenylacetic Acid SCHEMBL418537 0.77 SRC (0.59) L3MBTL1MEN1KMT2APTGS1TDP1
Diphenylacetic Acid SCHEMBL9750917 0.77 SRC (0.59) L3MBTL1MEN1KMT2APTGS1TDP1
Diphenylacetic Acid SCHEMBL8411440 0.77 SRC (0.59) L3MBTL1MEN1KMT2APTGS1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103936537-A Method for performing gold-catalyzed selective C-H bond functionalization on phenol and aniline UNIV EAST CHINA NORMAL 2014-07-23 CN disclosed
US-5128422-A Molding materials HUELS AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
EP-0468162-A1 Modified polyphenylene ether based thermoplastic moulding compositions HÜLS AKTIENGESELLSCHAFT (DE) 1992-01-29 EP disclosed
EP-0391030-A2 Polyphenylene ether-polycondensate-block copolymers and process for their preparation HÜLS AKTIENGESELLSCHAFT (DE) 1990-10-10 EP disclosed