Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 9/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9700480 | 0.88 | HTR2C (0.43) | HTR2AHTR2CDRD2 | |
| SCHEMBL9024819 | 0.86 | HTR2C (0.59) | HTR2AHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL9702282 | 0.79 | HTR2A (0.36) | HTR2AHTR2CDRD2 | |
| SCHEMBL9445199 | 0.76 | HTR2C (0.57) | HTR2AHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL9024725 | 0.76 | HTR2C (0.56) | HTR2AHTR2CDRD2 | |
| SCHEMBL9023838 | 0.74 | HTR2C (0.55) | HTR2AHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL9023939 | 0.74 | HTR2C (0.54) | HTR2AHTR2CDRD2 | |
| SCHEMBL9445153 | 0.73 | HTR2C (0.53) | HTR2AHTR2CDRD2 | |
| SCHEMBL9023464 | 0.73 | HTR2C (0.57) | HTR2AHTR2CDRD2 | |
| SCHEMBL9701571 | 0.73 | HTR2C (0.34) | HTR2AHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474012-A1 | 6,7-Dihydro-3-phenyl-1,2-benzisoxazol-4(5H)-ones and -ols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-03-11 | — | — | EP | disclosed |