Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 1.00 |
| ▸ | LAP3 | P28838 | 2/20 | 0.63 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.57 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701672 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL2475297 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL9702776 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL4732847 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL8334357 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL12821817 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL2474085 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL9614565 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL11496375 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL8470020 | 1.00 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513760-A2 | Use of biphosphonate squalene synthetase inhibitors in pharmaceutical compositions useful in lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | claimed |
| CN-101321824-A | Flame retardant polymer composition | 3M INNOVATIVE PROPERTIES CO (US) | 2008-12-10 | — | — | CN | disclosed |
| EP-0513760-A2 | Use of biphosphonate squalene synthetase inhibitors in pharmaceutical compositions useful in lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |