Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021773 | 0.93 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9022081 | 0.93 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9075439 | 0.89 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9022073 | 0.77 | ALDH1A1 (0.36) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| Ethametsulfuron Methyl SCHEMBL30116866 | 0.77 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| Ethametsulfuron Methyl SCHEMBL55796 | 0.77 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| Ethametsulfuron Methyl SCHEMBL29512476 | 0.77 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29376940 | 0.75 | MAPT (0.61) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL127064 | 0.75 | MAPT (0.61) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30534024 | 0.75 | MAPT (0.61) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |