Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 11/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480453 | 0.78 | MTNR1B (0.56) | MTNR1BMTNR1ATRPV1TP53LMNA | |
| SCHEMBL9703245 | 0.78 | KCNN2 (0.50) | MTNR1BTP53ALDH1A1LMNAGRIN2C | |
| Hydrochloric Acid SCHEMBL9700855 | 0.77 | KCNN2 (0.51) | MTNR1BTP53ALDH1A1LMNAGRIN2C | |
| SCHEMBL1159274 | 0.74 | MTNR1B (0.48) | MTNR1BMTNR1ATRPV1TP53NPC1 | |
| SCHEMBL12111488 | 0.73 | RXFP1 (0.52) | MTNR1BMTNR1ATP53LMNAHTT | |
| SCHEMBL12394443 | 0.72 | MTNR1B (0.49) | MTNR1BMTNR1ATP53LMNAGRIN2C | |
| SCHEMBL12394558 | 0.70 | MTNR1B (0.51) | MTNR1BMTNR1ATP53LMNA | |
| Hydrochloric Acid SCHEMBL9701984 | 0.69 | KCNN2 (0.52) | MTNR1BALDH1A1LMNAGRIN2CMAPT | |
| SCHEMBL10704433 | 0.69 | SMN1; SMN2 (0.51) | MTNR1BMTNR1ATRPV1NPC1MITF | |
| SCHEMBL12394466 | 0.69 | MTNR1B (0.49) | MTNR1BMTNR1ATP53LMNAGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014465-A1 | USE OF ANNULATED TETRAHYDROPYRIDINACETIC ACID DERIVATES FOR TREATING NEUROLOGICAL DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-03 | — | — | WO | disclosed |
| EP-0358957-A1 | Fused tetrahydropyridineacetic acid derivatives, process for their preparation, and use of such compounds for the cardioprotection | BOEHRINGER INGELHEIM KG (DE) | 1990-03-21 | — | — | EP | disclosed |