SCHEMBL9701854

SCHEMBL9701854

Cc1cc2ccc3ccc(C)c4ccc(c1)c2c34

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
HPGD P15428 3/20 0.68
HSD17B10 Q99714 3/20 0.68
TSHR P16473 3/20 0.68
TDP1 Q9NUW8 2/20 0.68
CYP3A4 P08684 2/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
CYP1A2 P05177 10/20 0.43
FYN P06241 2/20 0.42
ACHE P22303 2/20 0.42
AHR P35869 2/20 0.42
ERBB2 P04626 1/20 0.42
MAOA P21397 1/20 0.42
CYP2A6 P11509 6/20 0.40
LCK P06239 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16250698 0.85 ALDH1A1 (0.80) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL5746596 0.83 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL29653567 0.81 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL29351387 0.81 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL31297987 0.81 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL290363 0.81 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL20345297 0.80 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL1760730 0.80 CYP1A2 (0.59) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL4141419 0.79 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10TSHRTDP1
SCHEMBL28671077 0.79 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102702153-A Method for preparing high-purity 2,6-dimethyl-gamma-pyrone UNIV XIANGTAN 2012-10-03 CN claimed
CN-113728039-A Polylactic acid composition, method for producing the same, and product produced thereby 株式会社理光 2021-11-30 CN disclosed
CN-102238948-B Novel 4-(heterocycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and also in cosmetics GALDERMA RES & DEV 2015-03-25 CN disclosed
CN-102702153-A Method for preparing high-purity 2,6-dimethyl-gamma-pyrone UNIV XIANGTAN 2012-10-03 CN disclosed
EP-0501579-A1 Naphthalene lactones as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1992-09-02 EP disclosed