Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081934 | 0.88 | MAPT (0.64) | MAPK1TDP1L3MBTL1MAPTHTR1A | |
| SCHEMBL12745447 | 0.86 | HTR1A (0.63) | MAPK1TDP1L3MBTL1MAPTC5AR1 | |
| SCHEMBL8940493 | 0.86 | PPARG (0.52) | TDP1L3MBTL1C5AR1FFAR4 | |
| SCHEMBL12434156 | 0.82 | ESR1 (0.49) | MAPK1TDP1L3MBTL1MAPTCYP1A2 | |
| SCHEMBL10605002 | 0.81 | C5AR1 (0.52) | MAPK1TDP1L3MBTL1MAPTC5AR1 | |
| SCHEMBL28512565 | 0.81 | HTR1A (0.54) | MAPK1TDP1L3MBTL1MAPTHTR1A | |
| SCHEMBL12745444 | 0.81 | HTR1A (0.61) | MAPK1TDP1L3MBTL1MAPTC5AR1 | |
| SCHEMBL10604249 | 0.80 | MAPT (0.56) | MAPK1TDP1L3MBTL1MAPTC5AR1 | |
| SCHEMBL12745448 | 0.79 | HTR1A (0.59) | MAPK1TDP1L3MBTL1MAPTC5AR1 | |
| SCHEMBL17659021 | 0.78 | MAPT (0.53) | MAPK1TDP1L3MBTL1MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166398-A | Anticholesterol agents or atherosclerosis | WARNER-LAMBERT CO. (US) | 1992-11-24 | — | — | US | disclosed |