Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081934 | 0.89 | MAPT (0.64) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL27828907 | 0.82 | F2 (0.48) | LMNA | |
| SCHEMBL3608836 | 0.82 | FFAR4 (0.49) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL3610590 | 0.82 | SMN1; SMN2 (0.49) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL6097879 | 0.82 | MRGPRX4 (0.57) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL1285894 | 0.81 | FFAR4 (0.61) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL2912541 | 0.81 | MAPT (0.55) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL2900845 | 0.80 | FFAR4 (0.50) | MAPTTDP1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL9313845 | 0.79 | CTSV (0.50) | MAPTFFAR4CDK1CCNB1GSK3B | |
| SCHEMBL18831436 | 0.79 | SLC22A12 (0.52) | MAPTMAPK1MRGPRX4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166398-A | Anticholesterol agents or atherosclerosis | WARNER-LAMBERT CO. (US) | 1992-11-24 | — | — | US | disclosed |