Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20902773 | 1.00 | APP (0.50) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL19569862 | 1.00 | APP (0.50) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL8592959 | 0.97 | APP (0.52) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL177559 | 0.90 | APP (0.55) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL177845 | 0.87 | APP (0.52) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL177764 | 0.87 | APP (0.52) | APPLMNACYP2C19BLMSLC6A6 | |
| Succinamide SCHEMBL29069526 | 0.83 | EPHX2 (0.49) | APPCYP2C19SOAT1MEN1KMT2A | |
| SCHEMBL3359743 | 0.82 | APEX1 (0.42) | LMNACYP2C19SOAT1MEN1KMT2A | |
| SCHEMBL20894935 | 0.82 | APP (0.46) | APPLMNACYP2C19BLMSLC6A6 | |
| SCHEMBL3359740 | 0.82 | KMT2A (0.40) | LMNACYP2C19BLMSOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013843-A1 | SYNTHESIS OF INTERMEDIATES IN THE PREPARATION OF ACAT INHIBITORS | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |