Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177764 | 0.97 | APP (0.52) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL177845 | 0.97 | APP (0.52) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL8592959 | 0.92 | APP (0.52) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL20902773 | 0.90 | APP (0.50) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL19569862 | 0.90 | APP (0.50) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL9702032 | 0.90 | APP (0.50) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL177492 | 0.86 | — | — | |
| SCHEMBL177593 | 0.83 | BLM (0.46) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL177490 | 0.83 | BLM (0.46) | APPBLMCYP2C19LMNASLC6A6 | |
| SCHEMBL29045770 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | claimed |
| US-10201623-B2 | HSP90-targeted cardiac imaging and therapy | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2019-02-12 | — | — | US | claimed |
| US-20140088121-A1 | HSP90 Inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-03-27 | — | — | US | claimed |
| US-20240058482-A1 | USES OF LABELED HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2024-02-22 | — | — | US | disclosed |
| US-11661398-B2 | Cellular transport system for transferring a sulfonic acid construct carrying a cargo into the cytoplasm of a cell | Scientist of Fortune, S.A. (LU) | 2023-05-30 | — | — | US | disclosed |
| US-11607465-B2 | Uses of labeled HSP90 inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2023-03-21 | — | — | US | disclosed |
| CN-109071454-B | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2023-02-17 | — | — | CN | disclosed |
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-109374889-B | Use of labeled HSP90 inhibitors | 索隆-基特林癌症研究协会 | 2022-04-19 | — | — | CN | disclosed |
| CN-113521314-A | HSP 90-Targeted inflammation and infection imaging and treatment | 纪念斯隆-凯特琳癌症中心 | 2021-10-22 | — | — | CN | disclosed |
| US-20210308285-A1 | HSP90-TARGETED INFLAMMATION AND INFECTION IMAGING AND THERAPY | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-10-07 | — | — | US | disclosed |
| US-5338815-A | Used in thickeners, dispersion stabilizers and lubricants | SHOWA DENKO K.K. (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5300606-A | Crosslinked N-vinylamide resin | SHOWA DENKO K.K. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5280095-A | N-vinylcarboxylic acid amine resin | SHOWA DENKO K.K. (JP) | 1994-01-18 | — | — | US | disclosed |
| EP-0510246-A1 | Use of fine particulate crosslinked type n-vinylamide resin microgel | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1992-10-28 | — | — | EP | disclosed |
| EP-0473881-A1 | Liquid absorption agent | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1992-03-11 | — | — | EP | disclosed |
| EP-0215124-B1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-4925782-A | Silver halide photographic light-sensitive element containing water soluble dye compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4879204-A | HIGH CONTRAST | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0215124-A1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661398-B2 | Cellular transport system for transferring a sulfonic acid construct carrying a cargo into the cytoplasm of a cell | GOT1, GGCT, TGM2 | APP 4021/4885BLM 3378/4885CYP2C19 3074/4885 |
| US-20140088121-A1 | HSP90 Inhibitors | HSP90AB1, HSP90B1, HSP90AB2P | APP 3963/4885BLM 1490/4885CYP2C19 558/4885 |
| US-20240058482-A1 | USES OF LABELED HSP90 INHIBITORS | HSP90AB1, HSP90B1, HSP90AA1 | APP 4713/4885BLM 2589/4885CYP2C19 3730/4885 |
| US-10201623-B2 | HSP90-targeted cardiac imaging and therapy | HSP90AB1, HSP90AA1, HSP90B1 | APP 3551/4885BLM 3028/4885CYP2C19 1829/4885 |
| US-11607465-B2 | Uses of labeled HSP90 inhibitors | HSP90AB1, HSP90B1, HSP90AA1 | APP 4713/4885BLM 2589/4885CYP2C19 3730/4885 |
| US-20210308285-A1 | HSP90-TARGETED INFLAMMATION AND INFECTION IMAGING AND THERAPY | HSP90AB1, HSP90AA1, HSP90B1 | APP 1633/4885BLM 3846/4885CYP2C19 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.