Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146698 | 0.75 | — | — | |
| 4-Phenyl-Butylamine SCHEMBL132472 | 0.75 | MAOA (1.00) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| Biphenyl SCHEMBL9277907 | 0.73 | MAPT (0.44) | DAO | |
| SCHEMBL18628483 | 0.73 | BID (0.46) | MAOASIGMAR1DAO | |
| SCHEMBL23070514 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| SCHEMBL7865088 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| SCHEMBL130279 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| SCHEMBL8499165 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| SCHEMBL8499157 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 | |
| SCHEMBL5987924 | 0.73 | MAOA (0.95) | MAOAHTR2ASIGMAR1SMN1; SMN2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003732-A2 | COMPOSITIONS AND METHODS FOR ENHANCED BINDING IN BIOLOGICAL ASSAYS | BIOPROBE INTERNATIONAL, INC. (US) | 1992-03-05 | — | — | WO | disclosed |