Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715892 | 0.98 | RAB9A (0.53) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL9704090 | 0.89 | RAB9A (0.47) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL9703202 | 0.88 | RAB9A (0.68) | RAB9AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13340755 | 0.87 | RAB9A (0.59) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL23329317 | 0.83 | SMN1; SMN2 (0.46) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL9702798 | 0.82 | RAB9A (0.61) | RAB9AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9702829 | 0.82 | RAB9A (0.51) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL9702831 | 0.81 | RAB9A (0.50) | RAB9AKDM4ENISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL13514087 | 0.79 | KDM4E (0.79) | RAB9AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9704088 | 0.77 | RAB9A (0.61) | RAB9AKDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |