Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704963 | 0.99 | RAB9A (0.55) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL9705079 | 0.92 | RAB9A (0.61) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL9702249 | 0.89 | RAB9A (0.58) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742485 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742521 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742529 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742580 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742454 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742604 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL8742528 | 0.88 | RAB9A (0.62) | RAB9AKDM4ESMN1; SMN2NPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |