Butane

Butane

SCHEMBL9702464

CCCC.CCCC(N)OC(C)O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.35
METAP1 P53582 2/20 0.34
TSHR P16473 2/20 0.33
OPRM1 P35372 1/20 0.32
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31
TP53 P04637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL9701037 0.85 TSHR (0.39) SPHK1TSHRHSD17B10
SCHEMBL4997405 0.79 OPRM1 (0.35) METAP1TSHROPRM1
Ethylene Glycol SCHEMBL10954031 0.75 TSHR (0.36) SPHK1METAP1TSHRTP53
SCHEMBL10527685 0.73 OPRM1 (0.33) METAP1OPRM1
SCHEMBL4945280 0.72 TSHR (0.38) SPHK1TSHRHSD17B10
SCHEMBL2167547 0.72
SCHEMBL4440508 0.72
SCHEMBL11542103 0.71 TSHR (0.42) SPHK1METAP1TSHR
SCHEMBL8979932 0.70 OPRM1 (0.41) SPHK1METAP1OPRM1TP53
SCHEMBL21872713 0.70 TDP1 (0.45) SPHK1METAP1TSHROPRM1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5108880-A Developing agent, sulfite preservative and amino alcohol SUN CHEMICAL CORPORATION (US) 1992-04-28 US disclosed