Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702017 | 0.85 | PPARA (0.55) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL10457425 | 0.84 | PPARA (0.74) | PPARACYP1A2PPARGMEN1KMT2A | |
| SCHEMBL9702925 | 0.82 | PPARA (0.64) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL28138301 | 0.79 | PPARA (0.57) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL10641392 | 0.78 | PPARA (0.88) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL1143540 | 0.78 | MAOB (0.53) | CYP1A2SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL11088495 | 0.75 | PPARA (0.72) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11094581 | 0.75 | PPARA (0.64) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11097170 | 0.74 | PPARA (0.81) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL25353057 | 0.74 | PTGER4 (0.54) | PPARAMEN1KMT2ALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166398-A | Anticholesterol agents or atherosclerosis | WARNER-LAMBERT CO. (US) | 1992-11-24 | — | — | US | disclosed |