Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KMO | O15229 | 3/20 | 0.55 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | RHEB | Q15382 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957878 | 0.87 | KMO (0.72) | KMT2AKMOOXER1RHEBACLY | |
| SCHEMBL1576364 | 0.87 | KMO (0.72) | KMT2AKMOOXER1RHEBACLY | |
| SCHEMBL2006946 | 0.85 | HTR2A (0.55) | KMT2AKMOOXER1HTR2AHTR2C | |
| SCHEMBL9701399 | 0.85 | HTR2A (0.55) | KMT2AKMOOXER1HTR2AHTR2C | |
| SCHEMBL1576323 | 0.84 | KMO (0.78) | KMOOXER1HTR2AHTR2CACLY | |
| SCHEMBL416786 | 0.81 | KMO (0.65) | KMOOXER1HTR2AHTR2CACLY | |
| SCHEMBL27591506 | 0.81 | HTR2A (0.58) | KMOOXER1HTR2AHTR2CKRAS | |
| SCHEMBL4234811 | 0.81 | KMT2A (0.62) | KMT2APPARDPPARGPPARA | |
| SCHEMBL30103437 | 0.81 | KMT2A (0.62) | KMT2APPARDPPARGPPARA | |
| SCHEMBL29174329 | 0.80 | KMO (0.63) | KMT2AKMOOXER1RHEBACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065607-A1 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN RELATED PEPTIDASE 6 (KLK6) | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2018-04-12 | — | — | WO | disclosed |
| EP-3305781-A1 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6) | Deutsches Krebsforschungszentrum (DE) | 2018-04-11 | — | — | EP | disclosed |
| EP-3305781-A1 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6) | Deutsches Krebsforschungszentrum (DE) | 2018-04-11 | — | — | EP | disclosed |
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |