Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702562 | 0.85 | NMBR (0.47) | NMBRALDH1A1CYP3A4MAPTCTSL | |
| SCHEMBL9540282 | 0.75 | TACR1 (0.50) | — | |
| SCHEMBL9540278 | 0.75 | TACR1 (0.50) | — | |
| SCHEMBL23100729 | 0.69 | ECE1 (0.65) | KMT2AALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL23100728 | 0.69 | ECE1 (0.65) | KMT2AALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL8895674 | 0.67 | CTSL (0.55) | KMT2AALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL8098291 | 0.67 | NMBR (0.69) | NMBRMAPTACE | |
| SCHEMBL12052755 | 0.67 | NMBR (0.69) | NMBRMAPTACE | |
| SCHEMBL12062839 | 0.67 | NMBR (0.69) | NMBRMAPTACE | |
| SCHEMBL5380211 | 0.67 | NMBR (0.69) | NMBRMAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004038-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |