SCHEMBL9702605

SCHEMBL9702605

CN(C)C(=O)NC(N)=O.Clc1c(Cl)c2c(Cl)ccc3c4cccc5cccc(c(c1Cl)c23)c54.NC(=O)NC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
NCEH1 Q6PIU2 1/20 0.33
NPC1 O15118 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
APEX1 P27695 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
POLB P06746 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9153299 0.91 GAA (0.36) TSHRKDM4EGAAPOLBRXFP1
SCHEMBL10719426 0.85 CYP1A2 (0.35) KDM4EGAAPOLBRXFP1
SCHEMBL9151885 0.79 GAA (0.39) KDM4EGAAPOLBRXFP1
Bicarbonate SCHEMBL10434768 0.79 KMT2A (0.41) NPC1TSHRRAB9AKDM4EGAA
SCHEMBL9153114 0.78 GAA (0.35) KDM4EGAAPOLBRXFP1
SCHEMBL9516220 0.78 RXFP1 (0.37) TSHRKDM4EGAAPOLBRXFP1
SCHEMBL9515080 0.77 ALDH1A1 (0.41) TSHRKDM4EGAAPOLBRXFP1
SCHEMBL638889 0.77 CYP2A6 (0.41) TSHRKDM4EGAAPOLBRXFP1
SCHEMBL29565545 0.77 CYP2A6 (0.41) TSHRKDM4EGAAPOLBRXFP1
SCHEMBL10434905 0.74 KDM4E (0.35) KDM4EGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476416-A2 Method for the masking of plastics BAYER AG (DE) 1992-03-25 EP disclosed