Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9703241 | 0.88 | KMT2A (0.48) | MAOATSHRKMT2AMEN1BCHE | |
| SCHEMBL3763814 | 0.79 | MAPKAPK2 (0.35) | KMT2A | |
| SCHEMBL10903430 | 0.78 | MAOA (0.48) | MAOATSHRKMT2AMEN1BCHE | |
| SCHEMBL9703245 | 0.76 | KCNN2 (0.50) | MAOAGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL9700855 | 0.76 | KCNN2 (0.51) | MAOAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10642003 | 0.74 | MAOA (0.57) | MAOATSHRKMT2AMEN1BCHE | |
| SCHEMBL1819006 | 0.73 | MAOA (0.64) | MAOATSHRKMT2AMEN1BCHE | |
| Bromide SCHEMBL10706879 | 0.73 | MAOA (0.56) | MAOATSHRKMT2AMEN1BCHE | |
| Hydrochloric Acid SCHEMBL10636936 | 0.73 | MAOA (0.58) | MAOATSHRKMT2AMEN1BCHE | |
| Bisobrin SCHEMBL564266 | 0.72 | GRIN2D (0.55) | MAOATSHRKMT2ABCHEGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014465-A1 | USE OF ANNULATED TETRAHYDROPYRIDINACETIC ACID DERIVATES FOR TREATING NEUROLOGICAL DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-03 | — | — | WO | disclosed |
| EP-0358957-A1 | Fused tetrahydropyridineacetic acid derivatives, process for their preparation, and use of such compounds for the cardioprotection | BOEHRINGER INGELHEIM KG (DE) | 1990-03-21 | — | — | EP | disclosed |