Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633712 | 0.92 | FDPS (0.57) | FDPS | |
| Sq-34919 SCHEMBL9632781 | 0.89 | — | — | |
| Sq-34919 SCHEMBL9633342 | 0.89 | — | — | |
| Sq-34919 SCHEMBL9632769 | 0.89 | — | — | |
| SCHEMBL9631973 | 0.89 | — | — | |
| SCHEMBL9631967 | 0.89 | — | — | |
| SCHEMBL839903 | 0.86 | FDPS (0.52) | FDPS | |
| SCHEMBL9633372 | 0.84 | — | — | |
| SCHEMBL9632034 | 0.84 | — | — | |
| SCHEMBL9632023 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513760-A2 | Use of biphosphonate squalene synthetase inhibitors in pharmaceutical compositions useful in lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | claimed |
| EP-0513760-A2 | Use of biphosphonate squalene synthetase inhibitors in pharmaceutical compositions useful in lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |