Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703951 | 0.90 | TRPV1 (0.47) | ALDH1A1TRPV1 | |
| SCHEMBL9703944 | 0.90 | TRPV1 (0.47) | ALDH1A1TRPV1 | |
| SCHEMBL9703979 | 0.85 | MEN1 (0.38) | MEN1GAAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL9702126 | 0.83 | SMN1; SMN2 (0.57) | MEN1GAAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL9702167 | 0.82 | SMN1; SMN2 (0.40) | MEN1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9703934 | 0.81 | ALDH1A1 (0.41) | MEN1GAAKMT2ASMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10518451 | 0.79 | SMN1; SMN2 (0.40) | MEN1GAAKMT2ASMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10522142 | 0.78 | HTT (0.42) | MEN1GAAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL10688378 | 0.77 | TRPV1 (0.46) | ALDH1A1TRPV1 | |
| SCHEMBL9704877 | 0.77 | TRPV1 (0.46) | ALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0223512-B1 | 2-PYRIDYLACETIC ACID DERIVATIVE, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0223512-A2 | 2-Pyridylacetic acid derivative, preparation process thereof and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1987-05-27 | — | — | EP | disclosed |