Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.49 |
| ▸ | ABAT | P80404 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198357 | 0.96 | APP (0.62) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| Ethylene SCHEMBL9423752 | 0.84 | APP (0.48) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL8403813 | 0.81 | APP (0.62) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL31299762 | 0.81 | APP (0.62) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL27694001 | 0.78 | CYP2A6 (0.52) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL31267103 | 0.75 | CYP2A6 (0.48) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL29012716 | 0.75 | CYP2A6 (0.48) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL3397190 | 0.74 | APP (1.00) | APP | |
| SCHEMBL27384702 | 0.74 | KDM4E (0.48) | APPKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL20529121 | 0.73 | CYP2A6 (0.47) | APPKDM4EPTGS2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |