Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.45 |
| ▸ | ABAT | P80404 | 3/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198357 | 0.77 | APP (0.62) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Ethylene SCHEMBL9702983 | 0.74 | APP (0.59) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL10692423 | 0.72 | KDM4E (0.83) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL10421379 | 0.69 | ALDH1A1 (0.44) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL29196221 | 0.68 | KDM4E (0.91) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL29954180 | 0.67 | PTGS2 (0.59) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL5607630 | 0.67 | PTGS2 (0.59) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL29349539 | 0.67 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL36350 | 0.67 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL9512877 | 0.67 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074764-C | Benzoxazinone dopamine D4 receptor antagonists | WARNER LAMBERT CO (US) | 2001-11-14 | — | — | CN | disclosed |
| CN-1219930-A | Benzoxazinone dopamine D4 receptor antagonists | WARNER LAMBERT CO (US) | 1999-06-16 | — | — | CN | disclosed |