Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732948 | 0.80 | HTT (0.55) | ALDH1A1HTTPOLBGAACYP1A2 | |
| SCHEMBL29951097 | 0.75 | HTT (0.48) | ALDH1A1HTTPOLBGAACYP1A2 | |
| SCHEMBL7931633 | 0.74 | HTT (0.47) | ALDH1A1HTTPOLBGAACYP1A2 | |
| SCHEMBL27927882 | 0.71 | POLB (0.63) | ALDH1A1HTTPOLBGAACYP1A2 | |
| SCHEMBL10560076 | 0.70 | HTT (0.48) | ALDH1A1HTTPOLBGAACYP1A2 | |
| SCHEMBL15617618 | 0.70 | KMT2A (0.56) | HTTGAAKMT2AMEN1ACP3 | |
| SCHEMBL27916949 | 0.70 | CYP1A2 (0.47) | ALDH1A1HTTPOLBGAACYP1A2 | |
| Dinitrophenylene SCHEMBL29222862 | 0.70 | TSHR (0.57) | ALDH1A1HTTPOLBGAACYP1A2 | |
| Dinitrophenylene SCHEMBL27951720 | 0.69 | TSHR (0.77) | ALDH1A1HTTGAACYP1A2CYP2C19 | |
| SCHEMBL12237260 | 0.69 | KMT2A (0.56) | ALDH1A1HTTPOLBGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0431122-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| WO-1991000312-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-10 | — | — | WO | disclosed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |