Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192202 | 0.92 | MCHR1 (0.55) | MCHR1MAOBOPRM1OPRK1CNR2 | |
| SCHEMBL6872283 | 0.85 | MCHR1 (0.58) | MCHR1BCHEACHECNR2CNR1 | |
| SCHEMBL30379861 | 0.85 | ATM (0.50) | MCHR1MAOBCNR2 | |
| SCHEMBL16930318 | 0.84 | MCHR1 (0.51) | MCHR1OPRK1CNR2 | |
| SCHEMBL5743428 | 0.83 | MAOB (0.51) | MAOBOPRM1BCHEACHE | |
| SCHEMBL4022611 | 0.80 | MEN1 (0.51) | MCHR1MAOBACHECNR2 | |
| SCHEMBL7028389 | 0.78 | CNR2 (0.50) | MCHR1BCHEACHECNR2 | |
| SCHEMBL5745728 | 0.78 | MCHR1 (0.52) | MCHR1MAOBOPRM1OPRK1BCHE | |
| SCHEMBL2310681 | 0.77 | FKBP1A (0.51) | MCHR1BCHEACHECNR2 | |
| SCHEMBL11438901 | 0.76 | CA12 (0.51) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086051-A | 1H, 3H-pyrrolo[1,2-c]thiazole-7-carboxamide derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1992-02-04 | — | — | US | disclosed |