Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 3/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | NSD3 | Q9BZ95 | 5/20 | 0.54 |
| ▸ | NSD2 | O96028 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516216 | 0.96 | ADORA2A (0.62) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| SCHEMBL382916 | 0.92 | FGFR1 (0.66) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL28195884 | 0.86 | ADORA2A (0.72) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| Water SCHEMBL28104849 | 0.85 | ADORA2A (0.70) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| SCHEMBL28195881 | 0.83 | ADORA2A (0.71) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| SCHEMBL8207464 | 0.83 | ADORA2A (0.75) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| SCHEMBL2352757 | 0.81 | FGFR1 (0.86) | ADCY5ADORA2AADORA1ADORA2BFGFR1 | |
| SCHEMBL11222112 | 0.80 | ADORA2A (0.80) | ADCY5ADORA2AADORA1ADORA2BNSD3 | |
| SCHEMBL2638945 | 0.79 | ADORA2A (0.74) | ADCY5ADORA2AADORA1ADORA2BNSD3 | |
| SCHEMBL67131 | 0.79 | ADORA2A (0.74) | ADCY5ADORA2AADORA1ADORA2BNSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | disclosed |
| US-4808716-A | VIRICIDES OR CHEMICAL INTERMEDIATES | CESKOSLOVENSKA AKADEMIC VED (CS) | 1989-02-28 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |