Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | NSD3 | Q9BZ95 | 7/20 | 0.60 |
| ▸ | NSD2 | O96028 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703433 | 0.92 | ADCY5 (0.65) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL10516216 | 0.90 | ADORA2A (0.62) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL2023978 | 0.85 | FGFR1 (0.70) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL4364344 | 0.85 | ADORA2A (0.70) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL1920120 | 0.83 | FGFR1 (0.67) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL11222112 | 0.82 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BNSD3NSD2 | |
| SCHEMBL7165319 | 0.82 | NSD3 (0.71) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL23559498 | 0.82 | PI4KA (0.63) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL97602 | 0.82 | FGFR1 (0.65) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL15257630 | 0.82 | FGFR1 (0.62) | FGFR1SLC22A6ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 759 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230110614-A1 | HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS | ATOSSA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | claimed |
| EP-4125936-A1 | HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS | Atossa Therapeutics, Inc. (US) | 2023-02-08 | — | — | EP | claimed |
| WO-2021194890-A1 | HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS | ATOSSA THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | claimed |
| CN-102702147-B | The application of andrographolide analog and treatment thereof | 辽宁利锋科技开发有限公司 | 2016-06-08 | — | — | CN | claimed |
| EP-1504014-B1 | PROCESS FOR PREPARATION OF CYCLIC PRODRUGS OF PMEA AND PMPA | METABASIS THERAPEUTICS INC (US) | 2015-12-02 | — | — | EP | claimed |
| EP-2223927-B1 | Salts of a phosphonic acid based prodrug of PMEA | METABASIS THERAPEUTICS INC (US) | 2014-10-15 | — | — | EP | claimed |
| EP-2223927-A2 | Cyclic phosphonic acid based prodrugs of PMEA and its analogues | Metabasis Therapeutics, Inc. (US) | 2010-09-01 | — | — | EP | claimed |
| WO-2010028858-A1 | USE OF CIS-IMIDAZOLINES, PARTICULARLY NUTLINS, FOR TREATING CHEMO-RESISTANT CANCER DISEASES | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2010-03-18 | — | — | WO | claimed |
| US-7517858-B1 | Prodrugs of pharmaceuticals with improved bioavailability | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | claimed |
| EP-1532157-A4 | NOVEL PHOSPHONIC ACID BASED PRODRUGS OF PMEA AND ITS ANALOGUES | METABASIS THERAPEUTICS INC (US) | 2009-02-25 | — | — | EP | claimed |
| EP-0754046-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN, William R. (US) | 1997-01-22 | — | — | EP | claimed |
| EP-0533833-B1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1995026734-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN WILLIAM R (US) | 1995-10-12 | — | — | WO | claimed |
| EP-0647272-A1 | ANTI-HIV PROTEINS GAP 31, DAP 30 AND DAP 32, DNA CODING THEREFOR AND THERAPEUTIC USES THEREOF | NEW YORK UNIVERSITY (US) | 1995-04-12 | — | — | EP | claimed |
| EP-0647272-A4 | ANTI-HIV PROTEINS GAP 31, DAP 30 AND DAP 32, DNA CODING THEREFOR AND THERAPEUTIC USES THEREOF. | UNIV NEW YORK (US) | 1994-10-20 | — | — | EP | claimed |
| EP-0533833-A1 | PHOSPHOROUS PRODRUGS. | GLAZIER ARNOLD (US) | 1993-03-31 | — | — | EP | claimed |
| WO-1993004085-A1 | ANTI-HIV PROTEINS GAP 31, DAP 30 AND DAP 32, DNA CODING THEREFOR AND THERAPEUTIC USES THEREOF | NEW YORK UNIVERSITY (US) | 1993-03-04 | — | — | WO | claimed |
| WO-1991019721-A1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1991-12-26 | — | — | WO | claimed |
| WO-1990000555-A1 | LIPID DERIVATIVES OF ANTIVIRAL NUCLEOSIDES, LIPOSOMAL INCORPORATION AND METHOD OF USE | VICAL, INC. (US) | 1990-01-25 | — | — | WO | claimed |
| EP-0350287-A2 | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use | NeXstar Pharmaceuticals, Inc. (US) | 1990-01-10 | — | — | EP | claimed |