Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27382967 | 1.00 | LMNA (0.39) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL29385317 | 0.83 | LMNA (0.37) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL29498404 | 0.82 | LMNA (0.33) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL31059854 | 0.81 | LMNA (0.36) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL31059850 | 0.81 | LMNA (0.36) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL29282689 | 0.81 | LMNA (0.36) | LMNATSHRALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL27994511 | 0.81 | LMNA (0.36) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL518623 | 0.81 | DPP4 (0.33) | TSHR | |
| Methacrylic Acid SCHEMBL9704882 | 0.81 | TSHR (0.34) | TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL29285058 | 0.79 | LMNA (0.46) | LMNATSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222059-B1 | IMPROVED RADIATION-HARDENABLE DILUENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-07-08 | — | — | EP | claimed |