Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 4/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052187 | 0.91 | MAPT (0.46) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL11056544 | 0.90 | MAPT (0.49) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL11050765 | 0.90 | MAPT (0.49) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL11052185 | 0.90 | MAPT (0.49) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL11054342 | 0.90 | MAPT (0.49) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL11060479 | 0.89 | TSHR (0.50) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL116157 | 0.88 | TSHR (0.44) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL971960 | 0.85 | TSHR (0.41) | MAPTMAPK1HPGDTSHRFAAH | |
| SCHEMBL31742398 | 0.85 | TSHR (0.50) | MAPTMAPK1HPGDTSHRTHRB | |
| SCHEMBL14824482 | 0.84 | TSHR (0.51) | MAPTMAPK1HPGDTSHRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222059-B1 | IMPROVED RADIATION-HARDENABLE DILUENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-07-08 | — | — | EP | claimed |
| EP-0222059-A2 | Improved radiation-hardenable diluents | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-05-20 | — | — | EP | claimed |