SCHEMBL14824482

SCHEMBL14824482

C=CC(=O)OC(CO)COCCCC

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
HPGD P15428 1/20 0.51
PRKCA P17252 5/20 0.42
PRKCE Q02156 2/20 0.42
PRKCQ Q04759 2/20 0.42
PRKCD Q05655 2/20 0.42
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
PLA2G2C Q5R387 1/20 0.39
ATM Q13315 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10950542 0.98 TSHR (0.50) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL14828465 0.92 TSHR (0.44) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL14824448 0.86 TSHR (0.59) TSHRHPGDPLA2G2CATMTHRB
Hexane SCHEMBL9703643 0.84 MAPT (0.55) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL6423789 0.82 TSHR (0.53) TSHRHPGDUSP2PLA2G2CATM
SCHEMBL12131534 0.82 TSHR (0.33) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL11060479 0.81 TSHR (0.50) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL2359280 0.81 TSHR (0.55) TSHRHPGDPLA2G2C
SCHEMBL410384 0.81 TSHR (0.36) TSHRHPGDPRKCAPRKCEPRKCQ
SCHEMBL409945 0.81 TSHR (0.36) TSHRHPGDPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130085203-A1 (METH)ACRYLIC-MODIFIED ORGANOPOLYSILOXANE, RADIATION-CURABLE SILICONE COMPOSITION, SILICONE RELEASE LINER, AND MAKING METHODS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-04 US disclosed
US-20130085203-A1 (METH)ACRYLIC-MODIFIED ORGANOPOLYSILOXANE, RADIATION-CURABLE SILICONE COMPOSITION, SILICONE RELEASE LINER, AND MAKING METHODS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-04 US disclosed
EP-2574638-A1 (Meth)acrylic-Modified Organopolysiloxane, Radiation-Curable Silicone Composition, Silicone Release Liner, and Making Methods Shin-Etsu Chemical Co., Ltd. (JP) 2013-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130085203-A1 (METH)ACRYLIC-MODIFIED ORGANOPOLYSILOXANE, RADIATION-CURABLE SILICONE COMPOSITION, SILICONE RELEASE LINER, AND MAKING METHODS MMAB, IDUA, MSR1 TSHR 101/4885HPGD 1409/4885PRKCA 4559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.