Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705387 | 0.88 | CCKBR (0.38) | CCKBRBACE1APPGABRA1GABRG2 | |
| SCHEMBL9703566 | 0.83 | CCKBR (0.38) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9703671 | 0.66 | PTH1R (0.49) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| Dimethylamine SCHEMBL9651824 | 0.65 | MAPT (0.40) | CCKBRAPPCES2KDM4ENPC1 | |
| SCHEMBL9651820 | 0.64 | KMT2A (0.71) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9651814 | 0.64 | KMT2A (0.71) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9702894 | 0.63 | CCKBR (0.49) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9653091 | 0.62 | MEN1 (0.58) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6730982 | 0.61 | APP (0.46) | APPCES2PTGS1KDM4ENPC1 | |
| SCHEMBL8555730 | 0.59 | MAOB (0.39) | SLC6A4KDM4ENPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091381-A | Detection of peripheral benzodiazepine receptor activity in cell or tissue by labelled compounds using radioisotopes or cytoxic agents | BIOMEASURE, INC. (US) | 1992-02-25 | — | — | US | disclosed |