SCHEMBL9703729

SCHEMBL9703729

CC(=O)OCCN(C)CC(O)=S

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
MVD P53602 1/20 0.37
CHRM5 P08912 3/20 0.36
CHRM1 P11229 3/20 0.36
CHRM3 P20309 3/20 0.36
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PGR P06401 1/20 0.36
HTR1A P08908 1/20 0.36
TBXA2R P21731 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA10 Q9GZZ6 1/20 0.36
CHRNA9 Q9UGM1 1/20 0.36
TSHR P16473 1/20 0.36
GALR3 O60755 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16664455 0.84 MVD (0.50) ALDH1A1MVDCHRM5CHRM1CHRM3
SCHEMBL18827219 0.82 ALDH1A1 (0.41) ALDH1A1MVDCHRM5CHRM1CHRM3
SCHEMBL65062 0.81 ALDH1A1 (0.48) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL17401255 0.77 ALDH1A1 (0.44) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL14040573 0.75 ALDH1A1 (0.48) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL24490938 0.74 MEN1 (0.45) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL18211575 0.74 PIK3CD (0.43) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL11981282 0.74 ALDH1A1 (0.52) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL13236345 0.74 ALDH1A1 (0.41) ALDH1A1CHRM5CHRM1CHRM3CHRM2
SCHEMBL26298803 0.73 CHRM5 (0.34) ALDH1A1MVDCHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0194972-B1 NOVEL CYCLOSPORINS SANDOZ AG (CH) 1992-07-29 EP disclosed
EP-0194972-A2 Novel cyclosporins SANDOZ AG (CH) 1986-09-17 EP disclosed