Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295110 | 0.81 | HTR2A (0.53) | DRD2HTR2ADRD3 | |
| SCHEMBL2599486 | 0.77 | DRD2 (0.49) | DRD2HTR2ADRD3HTR1A | |
| Hydrochloric Acid SCHEMBL2599503 | 0.76 | DRD2 (0.48) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL27915442 | 0.73 | DRD2 (0.48) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL28106582 | 0.72 | DRD2 (0.43) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL10491761 | 0.72 | JAK2 (0.46) | DRD2HTR2ADRD3ADRB1HTR6 | |
| SCHEMBL29151771 | 0.71 | HTR2C (0.50) | DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL11136214 | 0.71 | JAK2 (0.45) | DRD2HTR2ADRD3ADRB1HTR6 | |
| SCHEMBL21254618 | 0.70 | HTR2A (0.60) | HTR2AHTR1A | |
| SCHEMBL10676145 | 0.70 | HTR2C (0.63) | HTR1AADRB1HTR6AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230179-B1 | 4-MORPHOLINYL 1H-INDOLE DERIVATIVES, THEIR SALTS, PROCESS AND INTERMEDIATES OF PREPARATION, USE AS THERAPEUTIC AGENTS, COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-09-30 | — | — | EP | claimed |
| US-4699907-A | ANTIISCHEMIC, HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1987-10-13 | — | — | US | claimed |
| US-4736042-A | CHEMICAL INTERMEDIATES | ROUSSEL UCLAF (FR) | 1988-04-05 | — | — | US | disclosed |
| US-4736042-A | CHEMICAL INTERMEDIATES | ROUSSEL UCLAF (FR) | 1988-04-05 | — | — | US | disclosed |
| US-4699907-A | ANTIISCHEMIC, HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1987-10-13 | — | — | US | disclosed |
| US-4699907-A | ANTIISCHEMIC, HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1987-10-13 | — | — | US | disclosed |
| US-4699907-A | ANTIISCHEMIC, HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1987-10-13 | — | — | US | disclosed |