Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703753 | 0.89 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10646921 | 0.85 | MAOB (0.34) | KDM4EHSD17B10ALDH1A1LMNATSHR | |
| SCHEMBL9704661 | 0.84 | DYRK1A (0.39) | DYRK1AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9703608 | 0.84 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9703318 | 0.82 | PLAT (0.35) | DYRK1APLATKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9703887 | 0.78 | ALDH1A1 (0.45) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL9703653 | 0.77 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9705497 | 0.77 | KDM4E (0.45) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9703286 | 0.76 | HPGD (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9703806 | 0.75 | KMT2A (0.43) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |