Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703962 | 1.00 | TRPV1 (0.42) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703934 | 0.91 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9704877 | 0.88 | TRPV1 (0.46) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL10688378 | 0.88 | TRPV1 (0.46) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703121 | 0.87 | TRPV1 (0.46) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703133 | 0.87 | TRPV1 (0.46) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703954 | 0.87 | TRPV1 (0.45) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703951 | 0.83 | TRPV1 (0.47) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9703944 | 0.83 | TRPV1 (0.47) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL9702676 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0223512-B1 | 2-PYRIDYLACETIC ACID DERIVATIVE, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0223512-A2 | 2-Pyridylacetic acid derivative, preparation process thereof and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1987-05-27 | — | — | EP | disclosed |