Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703786 | 0.90 | MEN1 (0.39) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9704171 | 0.80 | MAPK1 (0.40) | KDM4EMAPK1 | |
| SCHEMBL11260228 | 0.79 | KDM4E (0.42) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9704850 | 0.78 | MAPK1 (0.44) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9704329 | 0.78 | MAPK1 (0.44) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9705021 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2776008 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL10758398 | 0.71 | ALDH1A1 (0.47) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9705704 | 0.70 | KDM4E (0.42) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9704892 | 0.70 | MAPT (0.46) | KDM4EMEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |