SCHEMBL9703981

SCHEMBL9703981

CCOC(=O)C(N)=NNc1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.55
GPR35 Q9HC97 1/20 0.50
HPGD P15428 2/20 0.49
MAPT P10636 2/20 0.48
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 4/20 0.41
POLB P06746 1/20 0.41
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704223 1.00 ABCB1 (0.55) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9704778 0.88 ABCB1 (0.55) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9704137 0.88 ABCB1 (0.55) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL8440941 0.87 ABCB1 (0.58) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL7707113 0.87 ABCB1 (0.58) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9218647 0.84 ABCB1 (0.64) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9218656 0.84 ABCB1 (0.64) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9215583 0.83 ABCB1 (0.63) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9215587 0.83 ABCB1 (0.63) ABCB1GPR35HPGDMAPTALDH1A1
SCHEMBL9217495 0.81 ABCB1 (0.60) ABCB1GPR35HPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed